China Factory Direct
|
|
| CAS number | 211637-75-1 |
| Product name | FMOC-L-2-Methylphe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Drug synthesis intermediate | Used in solid-phase peptide synthesis (SPPS) as a protected amino acid monomer for constructing peptide sequences containing L-2-methylphenylalanine residues |
| Biotechnology | Peptide research reagent | Introduced via the Fmoc strategy to incorporate hydrophobic amino acids, enabling modulation of peptide conformation and biological activity |
| Organic chemistry | Chiral building block | Employed as a chiral starting material in asymmetric synthesis to prepare biologically active molecules with defined stereochemistry |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase with UV detection; L-isomer content determined by relative peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantify water via stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantification of common organic solvents (e.g., DMF, DCM, methanol). |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis after acid digestion, using inductively coupled plasma mass spectrometry for detection at sub-ppb levels. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities (e.g., FMOC-deprotected species, diastereomers) using gradient RP-HPLC. |
| Optical Rotation | [alpha]D Measurement | Specific rotation measured at 589 nm using a polarimeter; confirms chiral integrity and batch-to-batch consistency. |
| Residue on Ignition | Gravimetric Analysis | Mass loss after high-temperature ashing; residue weighed to determine inorganic ash content. |
| pH (1% w/v aqueous suspension) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volumetric particle size distribution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or via automated detection during controlled heating of solid sample. |
| Microbial Contamination | Membrane Filtration and Plate Count | Sample filtration followed by culture on tryptic soy agar; enumeration of aerobic mesophilic microorganisms. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -51.0 to -47.0 deg (c=1, DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.