5-chloropyrazine-2-carboxamide Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 21279-64-1 |
| Product name | 5-chloropyrazine-2-carboxamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 5-chloropyrazine-2-carboxamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-chloropyrazine-2-carboxamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-chloropyrazine-2-carboxamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key pharmaceutical intermediate | Used in the synthesis of antitumor agents such as famitinib—vascular endothelial growth factor receptor (VEGFR) inhibitors—by incorporating the pyrazine core structure into the target molecule. |
| Pharmaceutical Industry | Kinase inhibitor building block | Employed—via its amino group, or the carboxyl group after hydrolysis, or the halogenated pyrazine moiety—to construct kinase inhibitor libraries through amide bond formation, esterification, or Suzuki coupling reactions. |
| Agrochemical Industry | Intermediate for agrochemical synthesis | Serves as a nitrogen-containing heterocyclic scaffold for synthesizing novel insecticidal or fungicidal compounds. |
| Organic Synthesis | Specialized organic synthesis reagent | Enables selective nucleophilic substitution, hydrolysis, or reduction reactions—leveraging differential reactivity of the 2-position amide group and 5-position chlorine atom—to prepare other pyrazine derivatives. |
Manufacturing Quality Control of 5-chloropyrazine-2-carboxamide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine water content via stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract, calibrated against NaCl standard solutions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particles or discoloration against established reference samples. |
| Residue on Ignition | Gravimetric Analysis | Mass difference after high-temperature incineration to determine inorganic ash content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed dry or wet sample. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
Technical Specifications of 5-chloropyrazine-2-carboxamide
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 5-chloropyrazine-2-carboxamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-chloropyrazine-2-carboxamide
Safety Information of 5-chloropyrazine-2-carboxamide
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-chloropyrazine-2-carboxamide
Industrial 5-chloropyrazine-2-carboxamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply