4-NITROPHENYL ISOTHIOCYANATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2131-61-5 |
| Product name | 4-NITROPHENYL ISOTHIOCYANATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-NITROPHENYL ISOTHIOCYANATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-NITROPHENYL ISOTHIOCYANATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-NITROPHENYL ISOTHIOCYANATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate for preparing sulfur-containing pharmaceuticals or biologically active molecules | Introduces the isothiocyanate group via nucleophilic substitution and participates in coupling reactions to construct complex molecular architectures |
| Biochemistry | Protein labeling and probe conjugation | Undergoes specific reaction with primary amines on protein surfaces via the isothiocyanate group to enable fluorescent or functional labeling |
| Analytical Chemistry | Fluorescent probe or derivatization reagent for high-performance liquid chromatography (HPLC) analysis | Reacts with target compounds to generate detectable derivatives, enhancing detection sensitivity and selectivity |
| Materials Science | Surface functionalization of materials, including nanoparticle surface modification and polymer chain-end functionalization | Enables controlled grafting and functional modification through reaction of the isothiocyanate group with surface-bound amine groups |
Manufacturing Quality Control of 4-NITROPHENYL ISOTHIOCYANATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by HPLC-UV using gradient elution and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC-FID analysis to quantify common organic solvents (e.g., acetone, methanol, toluene) based on calibrated external standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content via stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator; measures free acidic impurities. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion and dilution, based on atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against calibration standards. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate and visual observation of solid-to-liquid phase change. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of particulates or discoloration against established reference samples. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under specified temperature and vacuum conditions for fixed duration. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution at specified concentration and wavelength (e.g., 589 nm). |
| Residue on Ignition | Gravimetric Ashing | Mass of non-volatile residue remaining after high-temperature incineration of sample in a platinum crucible. |
Technical Specifications of 4-NITROPHENYL ISOTHIOCYANATE
| Test Item | Specification |
|---|---|
| Appearance | Light orange to yellow to green crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-NITROPHENYL ISOTHIOCYANATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-NITROPHENYL ISOTHIOCYANATE
Packaging of 4-NITROPHENYL ISOTHIOCYANATE
Industrial 4-NITROPHENYL ISOTHIOCYANATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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