Methyl L-prolinate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2133-40-6 |
| Product name | Methyl L-prolinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl L-prolinate hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl L-prolinate hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl L-prolinate hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., oseltamivir) | Used for introducing protecting groups and as a chiral auxiliary in peptide synthesis |
| Agrochemicals | Synthesis of biologically active nitrogen-containing heterocyclic compounds | Employed as a chiral building block in asymmetric synthesis reactions |
| Fine Chemicals | Preparation of chiral catalysts or ligands | Used as a proline derivative precursor in organic synthesis, participating in reactions such as Michael addition and aldol condensation |
| Biochemical Research | Modeling proline metabolism or protein structural studies | Serves as a precursor for stable isotope-labeled compounds or as a starting material for probe molecule synthesis |
Manufacturing Quality Control of Methyl L-prolinate hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification via reversed-phase HPLC with UV detection at 200-210 nm using external standard calibration. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Separation and quantification of organic solvents (e.g., methanol, ethyl acetate) using flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion and plasma excitation. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on AgCl precipitation. |
| pH (1% aqueous solution) | pH Meter Measurement | Direct measurement of hydrogen ion activity in a 1% w/v aqueous solution at 25 C. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a standardized solution at 20 C and sodium D-line. |
| Loss on Drying | Gravimetric Analysis | Mass loss determined after drying at 105 C under vacuum or nitrogen for 2 hours. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium catalyst residues after microwave-assisted digestion. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
Technical Specifications of Methyl L-prolinate hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 138-142°C |
| Optical Rotation | -33.0 to -30.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl L-prolinate hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl L-prolinate hydrochloride
Safety Information of Methyl L-prolinate hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl L-prolinate hydrochloride
Industrial Methyl L-prolinate hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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