China Factory Direct
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| CAS number | 213475-52-6 |
| Product name | (S)-tert-Butyl 2-aMino-2-cyclohexylacetate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral auxiliary for chiral induction in asymmetric synthesis | Used as a recyclable chiral auxiliary in asymmetric transformations such as Diels–Alder, allylation, or alkylation reactions; introduced to control stereoselectivity and subsequently cleaved via acidolysis (e.g., HCl in organic solvent) |
| Fine chemicals | Chiral intermediate resolution and derivatization reagent | Applied in dynamic kinetic resolution (DKR) of racemic substrates or chiral derivatization for enantiomeric purity analysis or preparation of single-enantiomer intermediates |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (H-CHG-OTBU HCl content) | Acid-base titration with standardized NaOH | Quantifies the active compound by neutralizing the hydrochloride salt with strong base using phenolphthalein or potentiometric endpoint detection. |
| Water content | Karl Fischer titration | Measures trace water via iodine-sulfur dioxide redox reaction in anhydrous methanol-based solvent. |
| Residual solvents (e.g., THF, EtOAc, MeOH) | Gas chromatography (GC-FID) | Separates and quantifies volatile organic impurities using capillary column and flame ionization detection. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal elements by plasma ionization followed by mass spectrometric quantification at isotopic masses. |
| Chloride ion (Cl-) | Potentiometric titration with AgNO3 | Determines chloride concentration via argentometric titration using silver nitrate and a silver indicator electrode. |
| Related substances (impurity profile) | Reverse-phase HPLC-UV | Separates and quantifies structurally related impurities using C18 column, gradient elution, and UV detection at 210–254 nm. |
| Optical purity (enantiomeric excess) | Chiral HPLC | Resolves enantiomers on a chiral stationary phase and calculates ee from peak area ratio. |
| Residue on ignition | Gravimetric analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing (500–600 C) and weighing. |
| pH of aqueous solution (1% w/v) | pH meter measurement | Determines acidity/basicity of a standardized aqueous suspension using calibrated glass electrode. |
| Melting point | Capillary melting point apparatus | Identifies purity and identity by observing temperature range of solid-to-liquid phase transition under controlled heating. |
| Particle size distribution | Laser diffraction | Measures volume-weighted particle size distribution in dispersed dry or wet sample using Mie scattering theory. |
| Bulk density | USP <616> tap density method | Determines mass per unit volume after mechanical tapping to simulate industrial handling and storage behavior. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.