5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 213771-32-5 |
| Product name | 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pyridine-based pharmaceutical intermediates | Serves as a key structural unit in the synthesis of biologically active drug molecules—introducing aryl groups via Suzuki coupling, or undergoing further derivatization through hydrolysis, aminolysis, and related reactions. |
| Agrochemical Industry | Intermediates for agrochemical synthesis | Used to synthesize pyridine-ring-containing insecticides or herbicides; enables construction of lead compound libraries via functional group transformations. |
| Organic Synthesis | Construction and modification of pyridine-ring scaffolds | Enables cross-coupling reactions leveraging bromine reactivity, or selective chemical modifications of ester and methyl groups, to synthesize complex organic molecules. |
| Research Reagents | Materials for laboratory R&D | Applied in new drug screening, mechanistic studies of chemical reactions, and custom synthesis of small-molecule compounds. |
Manufacturing Quality Control of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, toluene, DMF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water by electrochemical or stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, with detection at sub-ppt levels. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration at 700-800 C followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating of a capillary-packed sample, observing solid-to-liquid phase change. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength. |
| Bulk Density | USP <616> Tap Density Tester | Determination of mass per unit volume after mechanical tapping to achieve settled state. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate size distribution based on Mie or Fraunhofer theory. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Electrode-based measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water). |
Technical Specifications of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
Safety Information of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester
Industrial 5-Bromo-3-methylpyridine-2-carboxylic acid methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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