2'-O-Methylcytidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2140-72-9 |
| Product name | 2'-O-Methylcytidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2'-O-Methylcytidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2'-O-Methylcytidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2'-O-Methylcytidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a nucleoside analog in antiviral drug development (e.g., HCV and HIV inhibitors) | Chemically modified from cytidine to incorporate a methoxy group, enhancing stability or target selectivity |
| Biotechnology | Employed in oligonucleotide synthesis (e.g., siRNA and antisense RNA modifications) to improve nuclease resistance or binding specificity | Used as a modified nucleoside monomer in solid-phase synthesis, incorporated into oligonucleotide chains via phosphoramidite chemistry |
| Research Reagents | Applied as reference standards or controls in metabolic pathway studies and epigenetic modification analysis | High-purity synthesis followed by HPLC purification for mass spectrometry or chromatographic analysis |
| Diagnostics | Potentially used as a label in viral detection probes (clinical validation required) | Conjugated with fluorescent labels to construct probes for pathogen nucleic acid detection via PCR or hybridization assays |
Manufacturing Quality Control of 2'-O-Methylcytidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of trace metal contaminants after acid digestion and plasma ionization. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution using anion-exchange column. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions in aqueous solution using anion-exchange column. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using polarimetry to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating. |
| Residue on Ignition | Gravimetric Analysis | Mass determination of non-volatile inorganic residue after high-temperature ashing. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens using selective culture media. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on light scattering pattern of dispersed sample. |
Technical Specifications of 2'-O-Methylcytidine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178~182°C |
| Optical Rotation | +69.6 to +72.3° (c=1, in water) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2'-O-Methylcytidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2'-O-Methylcytidine
Packaging of 2'-O-Methylcytidine
Industrial 2'-O-Methylcytidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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