2'-O-Methyluridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2140-76-3 |
| Product name | 2'-O-Methyluridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2'-O-Methyluridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2'-O-Methyluridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2'-O-Methyluridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesizing antiviral drugs (e.g., nucleoside analogs for hepatitis C treatment) | Chemical synthesis and purification |
| Biotechnology | Nucleotide precursor for RNA modification in mRNA vaccine or therapeutic RNA development | Enzymatic reaction and chromatographic separation |
| Research Reagents | Experimental use in studying nucleotide metabolism, RNA function, or viral replication mechanisms | Laboratory-scale synthesis and custom manufacturing |
Manufacturing Quality Control of 2'-O-Methyluridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 2'-methoxyuridine by reversed-phase HPLC with UV detection at ~265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separates and quantifies impurities (e.g., unreacted uridine, des-methoxy byproducts, degradation products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies residual solvents (e.g., methanol, DMF, ethyl acetate) by headspace gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water content via electrochemical titration using iodine generated in situ, based on the stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg, Ni) at trace levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700–800 °C followed by precise weighing of the residual residue. |
| Optical Rotation | Polarimetry | Measures specific optical rotation ([α]D) using sodium D-line light to confirm chiral integrity and identity. |
| pH of Solution (1% w/v) | pH Meter | Determines acidity/basicity of aqueous solution to detect acidic/basic degradation or residual reagents. |
| Microbial Contamination | Membrane Filtration / TSA/SDA | Assesses bioburden (total aerobic microbes, yeasts/molds) per pharmacopeial limits using culture-based enumeration. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form to ensure consistency in dissolution and handling properties. |
Technical Specifications of 2'-O-Methyluridine
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +40.0 to +44.0° (c=1, in water) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2'-O-Methyluridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2'-O-Methyluridine
Packaging of 2'-O-Methyluridine
Industrial 2'-O-Methyluridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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