China Factory Direct
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| CAS number | 2140-79-6 |
| Product name | 2'-O-Methyladenosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biotechnology | Raw material for RNA synthesis | Used in the synthesis of modified RNA, such as for mRNA vaccine production |
| Pharmaceutical R&D | Development of nucleoside analog drugs | Serves as a structural modification unit in antiviral or anticancer drugs |
| Food industry | Food additive | Applied for nucleic acid supplementation in specific functional foods |
| Medical diagnostics | Preparation of nucleic acid probes | Used for labeling or modification in molecular diagnostic kits |
| Chemical research | Organic synthesis intermediate | Applied in the synthesis of other nucleoside compounds or derivatives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 2'-O-methyladenosine by UV absorbance at 260 nm using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., adenosine, N6-methyladenosine) via gradient reverse-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after incineration at 700-800 C and subsequent weighing. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light to confirm chiral integrity and identity. |
| pH of Solution | Potentiometric pH Measurement | Measures pH of a defined aqueous solution (e.g., 1% w/v) using calibrated glass electrode and pH meter. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) by filtration, culture on selective media, and colony enumeration. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry powder form using Mie scattering theory and laser diffraction instrumentation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, confirming crystallinity and purity. |
| Identity Confirmation | FTIR Spectroscopy | Verifies molecular structure by comparing characteristic functional group absorption bands (e.g., ribose, methyl, adenine) against reference spectrum. |
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -59 to -55 deg (c=1, in H2O) |
| Melting Point | 205 to 210 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.