China Factory Direct
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| CAS number | 214210-21-6 |
| Product name | 3-Cyano-4-fluorobenzeneboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor, antiviral, or central nervous system drugs | Used in Suzuki-Miyaura coupling to construct aryl–aryl bonds |
| Pesticides | Precursor for synthesizing fluorinated aromatic heterocyclic insecticides or herbicides | Applied in palladium-catalyzed cross-coupling to introduce cyano and fluorinated aryl groups |
| Materials Science | Building block for organic optoelectronic materials (e.g., OLED emissive layers or electron-transport materials) | Employed in boronic acid-mediated cross-coupling to synthesize π-conjugated molecules |
| Fine Chemicals | Multifunctional synthon for modular assembly of complex molecules | Enables C–C bond formation via the boronic acid functional group, while preserving cyano and fluorine substituents for subsequent transformations |
| Test Item | Common Testing Method | Method Overview |
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| Appearance | Visual Inspection | Observe the sample's color, condition (e.g., white to off-white crystalline powder) and presence of foreign matter with the naked eye to determine if it meets quality standards. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 chromatographic column with an appropriate ratio of water-organic solvent (e.g., acetonitrile or methanol) as the mobile phase. Detect the main peak area using a UV detector (typically at 254 nm) to calculate the content of the main component and assess purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to the purity test conditions, use gradient elution to separate potential impurities (such as unreacted raw materials, by-products, and degradation products). Quantitative and qualitative analysis of impurities is performed using the normalized peak area method or reference substance method. |
| Moisture | Karl Fischer Titration | Determine the moisture content by reacting the sample with Karl Fischer reagent in a potentiometric titration. This method is suitable for borate compounds sensitive to moisture. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection methods with polar or non-polar capillary columns and FID detector to detect residual organic solvents (e.g., toluene, ethanol, dichloromethane) that may remain from synthesis or purification processes. |
| Melting Point | Capillary Melting Point Determination | Place the sample into a melting point capillary and observe the initial and final melting temperatures under controlled heating rate to verify physical property consistency. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) or Titration Method | ICP-OES can accurately determine total boron content; alternatively, acid-base titration combined with mannitol masking method can be used to indirectly determine the content of borate groups. |
| pH Value (if prepared as a solution) | pH Meter Measurement | Dissolve the sample in water to a specified concentration (e.g., 1%) and measure its acidity or alkalinity using a calibrated pH meter, reflecting the dissociation characteristics of boric acid. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | Detect trace amounts of harmful elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia or chemical safety standards. |
| Test Item | Specification |
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| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C to 152°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.