Methyl 3,4-dihydroxybenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2150-43-8 |
| Product name | Methyl 3,4-dihydroxybenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 3,4-dihydroxybenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 3,4-dihydroxybenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 3,4-dihydroxybenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediate | Used in organic synthesis reactions to produce cardiovascular drugs, including anti-anginal agents (e.g., Quexinshu) and expectorants (e.g., Rhododendrin) |
| Cosmetics Industry | Antioxidant and Preservative | Incorporated as an active ingredient in cosmetic formulations to scavenge free radicals and inhibit microbial growth, thereby preventing rancidity and delaying skin aging |
| Food Industry | Food Antioxidant | Added as a lipid-soluble antioxidant to oils, fats, butter, and food packaging materials to prevent oxidative rancidity |
| Organic Synthesis | Synthetic Building Block | Employed as a catechol derivative in transesterification and etherification reactions, or as a structural unit for synthesizing more complex pharmaceutical molecules |
| Research & Development | Physicochemical Property Studies | Used to evaluate antioxidant activity and free radical scavenging capacity, and as a reference standard or control substance in chromatographic analysis |
Manufacturing Quality Control of Methyl 3,4-dihydroxybenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~260 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV (with gradient elution) | Separation and quantification of structurally related impurities (e.g., 3,4-dihydroxybenzoic acid, methyl salicylate) using validated gradient HPLC-UV method. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual methanol, ethyl acetate, or toluene per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-pptr detection limits compliant with ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; sharp melting range indicates crystalline purity and identity. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | High-temperature incineration followed by gravimetric determination of inorganic residue, indicating inorganic impurity load. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity (though compound is achiral, detects potential chiral contaminants or degradation). |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a saturated aqueous suspension to assess acidic character and potential hydrolysis. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to ensure consistent bulk handling and dissolution behavior. |
| Microbial Limits | Membrane Filtration + Culture | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur. 5.1.4. |
Technical Specifications of Methyl 3,4-dihydroxybenzoate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 195–199 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 3,4-dihydroxybenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 3,4-dihydroxybenzoate
Packaging of Methyl 3,4-dihydroxybenzoate
Industrial Methyl 3,4-dihydroxybenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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