China Factory Direct
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| CAS number | 215190-22-0 |
| Product name | FMOC-PIPERAZINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a pharmaceutical intermediate for synthesizing various bioactive compounds | Target products are prepared via coupling reactions with amino acids or other organic molecules |
| Peptide Synthesis | Used as a key component in Fmoc-based protection strategies to protect the amino group on the piperazine ring | The Fmoc group is selectively removed under mild conditions (e.g., 20% piperidine in DMF), enabling stepwise peptide chain assembly |
| Cosmetics Industry | Involved in the synthesis of certain functional cosmetic ingredients | Typically incorporated as an intermediate step, depending on the final product’s formulation design |
| Fine Chemicals | Serves as a fundamental raw material for synthesizing other fine chemicals | May involve multiple chemical transformations—including but not limited to acylation and alkylation—depending on the target product |
| Biotechnology Research | Used as a building block in protein engineering | Applied in the design and synthesis of specific sequences to study protein structure–function relationships or develop novel biomaterials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (FMOC-Piperazine HCl) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 265 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, dichloromethane, methanol) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content by electrochemical reaction stoichiometry. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; quantifies metals (e.g., Pb, Cd, Ni, Fe) by atomic emission intensity at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a defined aqueous suspension (e.g., 1% w/v) using calibrated glass electrode. |
| Loss on Drying | Gravimetric Method | Weight loss after drying under controlled temperature and vacuum, indicating volatile content including residual solvents and moisture. |
| Residue on Ignition | Sulfated Ash Method | Ignition of sample with sulfuric acid followed by high-temperature ashing; residue mass reflects inorganic non-volatile impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as function of angle to determine volume-based particle size distribution. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; indicates chiral purity and identity. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (NMR) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178-182°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.