China Factory Direct
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| CAS number | 21543-49-7 |
| Product name | 2-Chloro-5-hydroxymethylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents | Specific functional groups introduced via substitution reactions |
| Agrochemicals | Synthetic precursor to pesticide active ingredients | Target compounds prepared via alkylation or acylation reactions |
| Chemical Manufacturing | Monomer for functional polymer synthesis | Pyridine-containing polymeric materials synthesized via polymerization |
| Analytical Reagents | Used in organic synthesis research and analytical testing | Purified for use as reference standards or probe reagents |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., 2-chloro-5-formylpyridine, unreacted pyridine derivatives) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, dichloromethane, toluene) by gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content via iodine-sulfur dioxide reaction in anhydrous methanol-based medium. |
| Chloride Ion Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using anion-exchange column and suppressed conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and Cr after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Measurement of mass loss after drying under specified temperature and vacuum conditions for fixed duration. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength (589 nm). |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size by measuring angular variation in intensity of laser light scattered by dispersed particles in liquid medium. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted identification and quantification of genotoxic impurities (e.g., alkyl chlorides) using gas chromatography coupled with mass spectrometric detection. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.