China Factory Direct
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| CAS number | 215453-51-3 |
| Product name | 7-BROMO-1-CHLOROISOQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serving as a synthetic intermediate for preparing candidate compounds for anticancer, antiviral, or neurological therapeutics | Introducing the isoquinoline scaffold via nucleophilic substitution or coupling reactions to construct complex molecular architectures |
| Organic Synthesis | Building libraries of nitrogen-containing heterocyclic compounds for high-throughput screening | Enabling selective functional group transformations by leveraging differential reactivity of bromine and chlorine atoms |
| Materials Science | Participating in the synthesis of optoelectronic materials or precursors for coordination polymers | Forming functional materials through metal-catalyzed cross-coupling or coordination-driven self-assembly |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column (e.g., C18) with methanol/water or acetonitrile/buffered salt as the mobile phase. The UV detector (e.g., 254 nm) quantifies the main component's purity and evaluates total impurity levels. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Employs a gradient program to separate the main peak from potential process impurities or degradation products. Impurity levels are calculated based on relative retention times and peak areas, ensuring compliance with pharmacopoeial limits. |
| Moisture Content | Karl Fischer Titration | Uses coulometric or volumetric Karl Fischer reagent to titrate trace amounts of water in the sample. Suitable for quality control of moisture-sensitive organic compounds. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection, capillary column separation, and FID or MS detection to quantify residual organic solvents (e.g., toluene, DMF), meeting ICH Q3C standards. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After acid digestion of the sample, detects residual levels of elements such as lead, cadmium, mercury, and arsenic to ensure compliance with safety limits for pharmaceutical or industrial raw materials. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirms molecular framework and substituent positions by comparing ¹H NMR and ¹³C NMR spectra with reference standards, verifying the correctness of the chemical structure. |
| Melting Point | Capillary Melting Point Apparatus | Determines the melting temperature range of the sample, serving as a physical constant to assist in assessing purity and crystalline form consistency. |
| Appearance and Characteristics | Visual Inspection + Microscopic Observation | Observes color, physical form (e.g., white to off-white crystals), and presence of foreign particles or caking to perform an initial assessment of whether the physical state meets specifications. |
| Loss on Drying | Weight Loss upon Drying (Constant Weight Method) | Dries the sample at a specified temperature (e.g., 105°C) until constant weight is achieved; calculates the percentage weight loss to reflect content of volatile components or adsorbed water. |
| Test Item | Specification |
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| Appearance | Pale-yellow Solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
| Total of impurities | Maximum 1.00 percent |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.