China Factory Direct
|
|
| CAS number | 21565-82-2 |
| Product name | 4-Pentynoic acid, methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key structural building blocks for synthesizing anticancer agents, protein kinase inhibitors, and other active pharmaceutical ingredients | Used as an alkynylation reagent in transition metal-catalyzed reactions, including Sonogashira coupling and Click reactions |
| Organic Synthesis | Construction of alkyne-containing complex molecular frameworks for total synthesis of natural products | Processed via derivatization reactions—including ester hydrolysis, reduction, and cycloaddition—to produce high-value compounds |
| Materials Science | Monomer for functional polymers and organic optoelectronic materials | Employed as a comonomer in free-radical polymerization or click chemistry polymerization to introduce alkyne functionality for material property modulation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and detector. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based solvent system. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of free carboxylic acid groups using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after controlled high-temperature ashing at 700-800 C. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of trace metal impurities by measuring absorption of characteristic atomic spectral lines in a flame or graphite furnace. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using anion-exchange column and conductivity detection. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement | Evaluation of sample color intensity against platinum-cobalt standard solutions using APHA scale at 455 nm. |
| Refractive Index | Refractometry | Measurement of light bending angle at air-sample interface using calibrated refractometer at specified temperature (e.g., 20 C). |
| Specific Gravity | Digital Density Meter or Pycnometry | Determination of mass-to-volume ratio relative to water at defined temperature (e.g., 25/25 C). |
| Distillation Range | Simple Distillation with Temperature Monitoring | Observation of initial and final boiling points under controlled atmospheric pressure using calibrated thermometer. |
| Residual Solvents (Methanol, Acetone) | Headspace Gas Chromatography (HS-GC) | Volatile organic impurity quantification via equilibrium headspace sampling followed by GC-FID analysis. |
| Related Substances (Impurity Profile) | Gas Chromatography-Mass Spectrometry (GC-MS) | Identification and semi-quantitative assessment of structurally related organic impurities using retention time and mass spectral matching. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.415–1.425 |
| Relative Density (20°C/25°C) | 0.910–0.930 g/cm³ |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.