D-VALINE METHYL ESTER HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 21685-47-2 |
| Product name | D-VALINE METHYL ESTER HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-VALINE METHYL ESTER HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-VALINE METHYL ESTER HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-VALINE METHYL ESTER HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate in the synthesis of antihypertensive drugs (e.g., valsartan) | Used as a chiral building block in peptide synthesis or asymmetric synthesis reactions |
| Pharmaceutical Manufacturing | Used in the preparation of active pharmaceutical ingredients (APIs) containing a valine moiety | Employed as a protected amino acid derivative in solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Used as a reference standard or probe in enzymology and metabolic studies | Applied in enzyme substrate specificity assays or metabolic pathway tracing experiments |
| Agricultural Chemicals | Synthesis of bioactive peptidomimetic pesticide intermediates | Used to construct agrochemical molecular scaffolds incorporating branched-chain amino acid structures |
Manufacturing Quality Control of D-VALINE METHYL ESTER HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Valine Methyl Ester Hydrochloride) | Acid-Base Titration with NaOH | Quantifies active compound by neutralizing HCl salt with standardized NaOH using potentiometric or visual endpoint detection. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; quantifies D-isomer purity via peak area ratio. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric reaction of iodine with water in pyridine/methanol medium. |
| Residual Solvents (Methanol, Ethyl Acetate) | Gas Chromatography (GC-FID) | Separates and quantifies volatile organic solvents using flame ionization detection against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal impurities by plasma ionization followed by mass spectrometric quantification at isotopic masses. |
| Chloride Content | Potentiometric Titration with AgNO3 | Determines chloride ions by titration with silver nitrate using silver indicator electrode and reference electrode. |
| Related Substances (Impurity Profile) | Reverse-Phase HPLC-UV | Separates and quantifies structurally related impurities using C18 column and UV detection at 210 nm. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual solids. |
| pH (1% Aqueous Solution) | pH Meter Measurement | Determines acidity/basicity of aqueous solution using calibrated glass electrode and reference electrode. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension by analyzing angular scattering pattern of laser beam. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Appearance and Color | Visual Inspection and Hazen Color Scale | Assesses physical state and color intensity by comparison to platinum-cobalt standard solutions under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Specific Optical Rotation | [a]D | Measures rotation of plane-polarized light at 589 nm to confirm chiral identity and purity using sodium lamp and polarimeter. |
Technical Specifications of D-VALINE METHYL ESTER HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | +12.0° to +14.0° (c=1, in 6N HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-VALINE METHYL ESTER HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of D-VALINE METHYL ESTER HYDROCHLORIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-VALINE METHYL ESTER HYDROCHLORIDE
Industrial D-VALINE METHYL ESTER HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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