China Factory Direct
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| CAS number | 216854-23-8 |
| Product name | (S)-3-N-Boc-aminopiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of targeted therapeutics (e.g., kinase inhibitors) | Chiral synthesis; Boc protection/deprotection reactions |
| Biochemistry | Protein structural studies and development of enzyme inhibitors | Solid-phase synthesis; molecular docking |
| Materials Science | Preparation of functionalized polymeric materials (e.g., controlled-release drug carriers) | Polymerization; nanoparticle surface modification |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and calculates enantiomeric excess from peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration using iodine generated electrochemically in a pyridine/methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion by measuring isotopic mass-to-charge ratios with high sensitivity. |
| Residual Palladium | ICP-MS | Specific quantification of palladium residues from catalytic hydrogenation steps using isotope-specific detection after sample digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection, calibrated against NaCl standards. |
| Sulfate Content | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column with conductivity detection, calibrated against Na2SO4 standards. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified vacuum and temperature conditions to determine volatile content. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., de-Boc, dimer, hydrolysis products) using gradient HPLC with UV detection. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -15.0 to -12.0 deg (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78 to 82 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.