China Factory Direct
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| CAS number | 21717-96-4 |
| Product name | 2-Amino-5-fluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor and antiviral agents | Used in organic synthesis and catalytic reactions |
| Pesticides | Active ingredient or intermediate in the production of fungicides and insecticides | Applied in condensation and fluorination reactions |
| Materials Science | Modified monomer for preparing fluorinated polymeric materials | Employed in polymerization and functionalization reactions |
| Dyes | Raw material for synthesizing fluorescent or functional dyes | Utilized in coupling and condensation reactions |
| Research Reagents | Organic building block for constructing complex molecular architectures | Used in laboratory-scale synthesis and purification |
| Test Item | Common Testing Methods | Method Overview |
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| Identification | Infrared Spectroscopy (IR) | By measuring the infrared absorption spectrum of the sample and comparing it with the standard spectrum, the characteristic functional groups of 2-Amino-5-fluoropyridine (such as N–H, C–F, aromatic ring, etc.) are confirmed by checking whether the absorption peak positions match. |
| Identification | Proton Nuclear Magnetic Resonance (¹H NMR) | Nuclear magnetic resonance is used to determine the chemical shift, integration area, and coupling constants of hydrogen atoms in the sample. The molecular structure is verified by comparing with the theoretical spectrum. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | A reverse-phase C18 column is used, with a mobile phase consisting of methanol/water or acetonitrile/buffer salt. An ultraviolet detector (typically at around 254 nm) is used for detection, and external or internal standard methods are applied for quantification of the main component. |
| Related Substances (Impurity) Check | High-Performance Liquid Chromatography (HPLC) | Similar chromatographic conditions are used as for content determination. The main peak and potential impurity peaks are separated by gradient elution or isocratic elution. Area normalization or a main component self-control method with correction factors is used to control the limits of each impurity. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used, with a polar or non-polar capillary column and an FID detector. Qualitative and quantitative analysis of residual organic solvents (such as methanol, dichloromethane, DMF, etc.) from the synthesis process is performed according to pharmacopoeia or ICH guidelines. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | The sample is dried to constant weight at a specified temperature (e.g., 105°C), and the mass percentage loss due to moisture or other volatile components is measured. |
| Melting Point | Capillary Melting Point Determination | The melting point is determined using a melting point apparatus, and the temperature range from initial melting to complete melting is compared with literature values (approximately 120–123°C) to assess purity and crystalline consistency. |
| pH Value (if prepared as a solution) | pH Meter Method | The sample is prepared into a solution of a certain concentration (e.g., 1% w/v), and the pH is measured using a calibrated pH meter, reflecting the presence of free acid/base or hydrolysis products. |
| Water Content | Karl Fischer Titration | Capacity or coulometric Karl Fischer titration is used to specifically determine the trace water content in the sample, which is suitable for quality control of moisture-sensitive raw materials. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 42–46°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.