4-Amino-3-chlorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 21803-75-8 |
| Product name | 4-Amino-3-chlorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-3-chlorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-3-chlorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-3-chlorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of dopamine receptor antagonists, such as chlorpromazine hydrochloride | Condensation and substitution reactions |
| Agrochemicals | Key intermediate in the synthesis of high-efficacy insecticides and fungicides | Catalytic hydrogenation and halogenation |
| Chemicals | Intermediate in the synthesis of dyes and functional materials | Coupling and diazotization reactions |
Manufacturing Quality Control of 4-Amino-3-chlorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., 4-amino-benzonitrile, 3-chloro-4-nitrobenzonitrile) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) to quantify volatile organic solvents (e.g., methanol, acetone, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in a pyridine-free reagent system for precise trace moisture measurement. |
| Heavy Metals | ICP-MS or ICP-OES | Multi-element quantitative analysis after acid digestion; detects toxic elements (e.g., Pb, Cd, Hg, As) at sub-ppb to ppb levels. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion exchange chromatography with conductivity detection, or argentometric titration using AgNO₃ to quantify inorganic chloride impurities. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating; assesses crystallinity and identity by comparison to literature value (~112–114 °C). |
| Appearance & Color | Visual Inspection & APHA Color Scale | Subjective evaluation of physical state (crystalline solid) and color intensity against platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 °C) in a muffle furnace. |
| pH of Aqueous Suspension | pH Meter Measurement | Determination of surface acidity/basicity by measuring pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine D10, D50, D90 values per ISO 13320. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution to confirm chiral purity (though compound is achiral, used to detect chiral contaminants). |
Technical Specifications of 4-Amino-3-chlorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-3-chlorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-3-chlorobenzonitrile
Packaging of 4-Amino-3-chlorobenzonitrile
Industrial 4-Amino-3-chlorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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