2-FLUORO-5-FORMYLBENZONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 218301-22-5 |
| Product name | 2-FLUORO-5-FORMYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-FLUORO-5-FORMYLBENZONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-FLUORO-5-FORMYLBENZONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-FLUORO-5-FORMYLBENZONITRILE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Prepared via organic synthesis methods, such as nucleophilic substitution and acylation |
| Pesticides | Synthesis of pesticide intermediates | Used as organic synthetic intermediates in the development of novel pesticides |
| Polymers | Synthesis of functional polymeric materials | Applied in the preparation of polymeric materials with specialized properties |
| Analytical Chemistry | Synthesis of reference standards or reagents | Used as certified reference materials in chromatographic analysis or chemical testing |
| Chemical Research | Investigation of compound reactivity | Employed as a model compound for mechanistic studies in organic synthesis |
Manufacturing Quality Control of 2-FLUORO-5-FORMYLBENZONITRILE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Form | Visual Inspection + Melting Point Determination | Observe sample color and state (typically white to pale yellow crystalline solid), determine melting point range (literature value approximately 85–90°C) to assess purity and crystallinity. |
| Assay (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with acetonitrile-water (containing 0.1% formic acid) as the mobile phase, UV detector at 254 nm, and external standard method for quantification; assess main component purity (typically required ≥98%). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used with a capillary column (e.g., DB-624) and FID detector, following ICH Q3C guidelines to detect residual solvents (e.g., DMF, acetonitrile, toluene). |
| Fluorine Content | Ion Chromatography (IC) or Oxygen Bomb Combustion with Ion-Selective Electrode | Sample is converted into fluoride ions via alkaline fusion or oxygen bomb combustion, followed by determination using ion chromatography or fluoride ion-selective electrode to ensure fluorine content matches theoretical value (theoretical F% ≈ 8.7%). |
| Impurity Profile Analysis | HPLC-MS / UPLC-MS | Use ultra-performance liquid chromatography coupled with mass spectrometry to identify and quantify structurally related impurities (e.g., hydrolysis product 2-fluoro-5-cyanobenzoic acid, unreacted starting material 2-fluoro-5-bromobenzonitrile), enabling comprehensive impurity profiling. |
| Moisture Content | Karl Fischer Titration | Determine trace moisture content accurately (typically required ≤0.5% w/w) using coulometric or volumetric Karl Fischer reagent titration to prevent hydrolysis or storage stability issues. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Dissolve sample in acetonitrile or methanol and measure absorption spectrum over 200–400 nm; characteristic absorption peaks appear around 230–250 nm (π→π\*) and 280–300 nm (n→π\*), useful for identification and concentration estimation. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as Pb, Cd, Hg, and As using AAS or inductively coupled plasma mass spectrometry (ICP-MS), ensuring compliance with ICH Q3D limits (e.g., ≤10 ppm). |
| Chloride/Sulfate Impurities | Colorimetric Method or Ion Chromatography | Detect chloride ions using silver nitrate colorimetry, sulfate ions using barium chloride colorimetry, or quantify via IC to ensure inorganic anion impurities meet pharmaceutical-grade specifications (e.g., ≤50 ppm). |
Technical Specifications of 2-FLUORO-5-FORMYLBENZONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-FLUORO-5-FORMYLBENZONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-FLUORO-5-FORMYLBENZONITRILE
Safety Information of 2-FLUORO-5-FORMYLBENZONITRILE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-FLUORO-5-FORMYLBENZONITRILE
Industrial 2-FLUORO-5-FORMYLBENZONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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