China Factory Direct
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| CAS number | 218780-53-1 |
| Product name | 1-N-(Methylsulfonyl)-4-piperidinone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of pharmaceuticals, including antiviral agents | Reacted with corresponding amines to generate target compounds |
| Chemical Manufacturing | Key raw material for organic synthesis | Participates in various organic reactions, including condensation and substitution |
| Research & Development | Tool molecule used in laboratory research | Employed to investigate new chemical reaction pathways or mechanisms |
| Drug Development | Used in the development of novel therapeutic agents | Subjected to specific chemical modifications followed by biological activity evaluation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, methanol, DMF) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for high sensitivity and specificity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions following sample dissolution and dilution. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after controlled ashing at 600-750 C to assess inorganic non-volatile impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | pH Meter | Potentiometric measurement of pH in a saturated aqueous suspension (1% w/v) at 25 C. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.