China Factory Direct
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| CAS number | 219138-02-0 |
| Product name | Z-IETD-AFC |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biotechnology | Fluorescent substrate for detection of caspase activity | Used as an in vitro assay reagent following chemical synthesis |
| Pharmaceuticals | Research on development of caspase inhibitors | Employed as an intermediate in drug screening and optimization |
| Research | Tool compound for apoptosis studies | Applied in quantitative analysis via fluorescent labeling techniques |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 300-320 nm. |
| Identity | LC-MS | Confirmation of molecular mass and fragmentation pattern matching the theoretical structure of Z-Ile-Glu-Thr-Asp-AFC. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., DMF, DCM, MeOH) using capillary column gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppt sensitivity. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deletion peptides, diastereomers, hydrolysis products) using gradient RP-HPLC. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at 20 degrees C using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Residual Peptide Coupling Reagents | HPLC-UV | Quantification of common coupling agents (e.g., HOBt, DIC residues) via validated reversed-phase HPLC method with UV detection. |
| Microbial Contamination | Membrane Filtration / TSA | Enumeration of aerobic microorganisms using membrane filtration followed by incubation on tryptic soy agar per USP <61>. |
| pH (1% w/v solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via Mie scattering theory using automated laser diffraction instrument. |
| Endotoxin Level | LAL Kinetic Turbidimetric Assay | Quantification of bacterial endotoxins using Limulus amebocyte lysate reagent and kinetic measurement of turbidity development. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C |
| Optical Rotation | -15.0 to -22.0 ° (c=1, in 0.1N HCl) |
| Residue on Ignition | <=0.3% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.