China Factory Direct
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| CAS number | 21943-12-4 |
| Product name | 2-Amino-3-bromopyrazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in drug synthesis, used to produce targeted anticancer agents such as tyrosine kinase inhibitors | Used in organic synthesis to construct drug molecular scaffolds via nucleophilic substitution, coupling reactions, and related steps |
| Materials Science | Synthesis of functionalized pyrazine-based organic materials, including electron-transport materials and ligands | Employed as a precursor in Suzuki coupling and other reactions to prepare conjugated molecules or metal–organic frameworks (MOFs) |
| Pesticide Development | Synthetic intermediate for insecticides or herbicides, enabling structural modification to optimize biological activity | Functionalized via etherification, alkylation, and related reactions at halogen sites to introduce specific functional groups |
| Academic Research | Basic chemical reagent for synthetic studies of pyrazine derivatives | Used in laboratory settings to investigate novel organic reaction mechanisms or to build libraries of heterocyclic compounds |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water; endpoint detected potentiometrically. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for ultra-trace sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions after sample dissolution and filtration; quantified against chloride calibration standards. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing at 700-800 C, expressed as percentage weight loss. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically during controlled heating; reported as onset and clear point range. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light (589 nm) in solution; indicates chiral purity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to calculate volume-based particle size distribution in dispersed dry or wet samples. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of pH in a defined suspension (e.g., 1% w/v in water) using a calibrated glass electrode and pH meter. |
| Bulk and Tapped Density | Carr Index Method | Determination of bulk density (loose powder) and tapped density (after standardized mechanical tapping), used to calculate compressibility and flowability. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 128°C - 132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.