6-Bromocoumarin-3-carboxylic acid is widely employed in the field of organic optoelectronic materials for the synthesis of fluorescent dyes and OLED emissive layer materials. It also serves as a key raw material for fluorescent labeling reagents in analytical chemistry and for constructing biosensing probes, meeting industrial-scale packaging requirements for direct factory supply.

Catalog

6-BROMOCOUMARIN-3-CARBOXYLIC ACID Bulk Supply for Industrial Use

China Factory Direct
	CAS number	2199-87-3
	Product name	6-BROMOCOUMARIN-3-CARBOXYLIC ACID
	Stock	Stock readily available; annual supply capacity exceeding 1,000 tons.
	Grade	Electronic GradeMaterial GradeReagent Grade
	Packaging	25KG/bag500KG/bag1000KG/bag
	Sample	Test Samples Available (Click to Request Samples)
	COA	View COA
	Price	Get Quote
	Supply Type	Bulk / Contract manufacturing / OEM
	Shipping	FCL / LCL available
	Payment Terms	Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
	Manufacturer	Greenrock Chemical(China Factory)

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CAS No:2199-87-3

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Documents We Provide for 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart

Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.

Bulk 6-BROMOCOUMARIN-3-CARBOXYLIC ACID Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

Industry	Application	Process
Pharmaceutical Intermediates	Structural building block for synthesizing anticoagulants, anticancer agents, and fluorescent probes	Serves as a key intermediate in multistep organic synthesis; bromo and carboxylic acid functionalities are commonly modified via Suzuki coupling, Heck reaction, or esterification/hydrolysis
Organic Optoelectronic Materials	Preparation of fluorescent dyes and OLED emissive layer materials	Bromo group enables metal-catalyzed cross-coupling to introduce conjugated moieties; carboxylic acid group anchors to metal oxide surfaces or is further derivatized into amide/ester functional molecules
Analytical Chemistry	Construction of fluorescent labeling reagents and biosensing probes	Carboxyl group reacts with amino groups of biomolecules (e.g., proteins, nucleic acids) via EDC/NHS-mediated condensation; bromo group allows selective modification to tune fluorescence properties

Manufacturing Quality Control of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

Detection Item	Common Analytical Method	Method Overview
Assay (Purity)	HPLC-UV	Quantifies main component by UV absorbance at specific wavelength using reverse-phase C18 column and calibrated standard.
Related Substances	HPLC-UV	Detects and quantifies structurally related impurities (e.g., unreacted 6-bromocoumarin, hydrolysis products) via gradient elution and peak area comparison.
Residual Solvents	GC-FID	Measures trace organic solvents (e.g., DMF, methanol, ethyl acetate) using flame ionization detection after headspace or direct injection.
Water Content	Karl Fischer Titration	Determines water by coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction in pyridine/methanol medium.
Heavy Metals	ICP-MS	Quantifies trace metal impurities (e.g., Pd, Ni, Fe) using inductively coupled plasma mass spectrometry with isotopic detection and internal standard correction.
Melting Point	Capillary Melting Point Apparatus	Determines temperature range of solid-to-liquid phase transition using calibrated capillary tube under controlled heating rate.
Residue on Ignition	Gravimetric Analysis	Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue.
Chloride Impurity	Ion Chromatography (IC)	Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection.
Optical Rotation	[α]D Measurement	Determines specific rotation at 589 nm using sodium D-line to confirm chiral integrity (if applicable; note: compound is achiral, but method verifies absence of chiral contaminants).

Technical Specifications of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

Test Item	Specification
Appearance	White to off-white crystalline powder
Purity	>=98.5%
Melting Point	162-166°C
Total Impurities	<=1.5%
Single Impurity	<=0.5%
Water Content (KF)	<=0.5%
Residue on Ignition	<=0.1%
Heavy Metals	<=10 ppm
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

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NMR Spectra of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

Safety Information of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

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Safety Data Sheet

Packaging of 6-BROMOCOUMARIN-3-CARBOXYLIC ACID

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial 6-BROMOCOUMARIN-3-CARBOXYLIC ACID Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

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