2-Methyl-L-proline Methyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 220060-08-2 |
| Product name | 2-Methyl-L-proline Methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Methyl-L-proline Methyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Methyl-L-proline Methyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Methyl-L-proline Methyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate in chiral synthesis for preparation of multiple drug molecules | Chiral catalytic synthesis, asymmetric synthesis |
| Chemicals | Key chiral building block in organic synthesis | Asymmetric synthesis reactions |
| Research & Development | Used in laboratories to explore new chemical reaction pathways and synthesize biologically active compounds | Chiral synthesis techniques, drug discovery research |
Manufacturing Quality Control of 2-Methyl-L-proline Methyl ester hydrochloride
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compares the infrared absorption spectrum of the sample with standard reference spectra to confirm the presence of characteristic functional groups (e.g., ester groups, secondary amine hydrochloride). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyzes chemical shifts, integration areas, and coupling constants of hydrogen atoms to verify molecular structure and stereoconfiguration (S configuration). | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with UV detection (e.g., 210–220 nm), employing external standard or area normalization methods to determine the main component content. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Uses the same conditions as content determination or gradient elution programs to separate and quantify potential process impurities, degradation products, and enantiomeric impurities. |
| Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Utilizes chiral stationary phase columns to separate (S) and (R) enantiomers, assessing optical purity (typically requiring ee ≥ 98%). |
| Moisture Content | Karl Fischer Titration | Determines water content using either titration (volumetric) or coulometric Karl Fischer methods, controlling crystallization water or hygroscopic moisture. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with FID detection; follows ICH Q3C guidelines to detect residual organic solvents (e.g., methanol, dichloromethane, ethanol) from synthesis or purification processes. |
| Melting Point | Melting Point Determination Method | Measures the melting temperature range using a melting point apparatus, serving as a physical constant for identification and purity assessment. |
| Specific Rotation | Polarimetry | Determines specific rotation at a specified wavelength (usually sodium D line, 589 nm) and concentration to verify chirality and optical purity. |
| pH (Solution) | pH Meter Measurement | Prepares a solution at a defined concentration and measures pH using a calibrated pH meter, reflecting the acidic characteristics of the hydrochloride salt. |
| Ignited Residue / Sulfated Ash | Gravimetric Method | After high-temperature ignition, weighs the inorganic residue to assess total inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial limits. |
Technical Specifications of 2-Methyl-L-proline Methyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -61.0 to -59.0° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 128 to 132°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Methyl-L-proline Methyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Methyl-L-proline Methyl ester hydrochloride
Safety Information of 2-Methyl-L-proline Methyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Methyl-L-proline Methyl ester hydrochloride
Industrial 2-Methyl-L-proline Methyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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