3',4',5'-TRIFLUOROACETOPHENONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 220141-73-1 |
| Product name | 3',4',5'-TRIFLUOROACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3',4',5'-TRIFLUOROACETOPHENONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3',4',5'-TRIFLUOROACETOPHENONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3',4',5'-TRIFLUOROACETOPHENONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing anticancer drugs (e.g., BTK inhibitors) | Prepared via Friedel–Crafts acylation or aromatic ring fluorination modification |
| Agrochemical Intermediates | Structural building block for synthesizing fluorinated insecticides and fungicides | Active molecular scaffold constructed through multi-step reactions including reduction and amination |
| Organic Synthesis | Fluorinated aryl ketone building block for constructing complex fluorinated compounds | Participates in transition metal-catalyzed reactions such as Grignard reactions, reductive amination, and Suzuki coupling |
Manufacturing Quality Control of 3',4',5'-TRIFLUOROACETOPHENONE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard illumination. Typically appears as a colorless to pale yellow liquid. |
| Content/Purity | Gas Chromatography (GC) | Uses a capillary column to separate components, detected by a flame ionization detector (FID). Main component content is calculated using area normalization or external standard method. Suitable for volatile organic compounds. |
| Content/Purity | High-Performance Liquid Chromatography (HPLC) | Applicable to thermally unstable or non-volatile samples. Employs a reversed-phase C18 column with a UV detector (typically at 254 nm). Quantification is performed using external standard or internal standard methods. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹⁹F NMR are used to confirm molecular structure and substitution positions, verifying the chemical identity of the target compound. |
| Structure Confirmation | Mass Spectrometry (MS) | Uses electron ionization (EI-MS) or electrospray ionization (ESI-MS) to determine molecular ion peaks, confirming molecular weight and fragmentation patterns. |
| Water Content | Karl Fischer Titration | Based on the quantitative reaction of iodine and sulfur dioxide with water in methanol. Quantifies water content via coulometric titration with high precision. |
| Residual Solvents | Gas Chromatography (GC) | According to pharmacopeial standards (e.g., Chinese Pharmacopoeia, USP), detects organic solvents potentially residual from manufacturing (e.g., methanol, ethanol, acetone). Uses headspace sampling coupled with FID detection. |
| Melting Point / Boiling Point | Melting Point Apparatus / Boiling Point Apparatus | Measures physical constants for auxiliary identification. 3,4,5-Trifluoroacetophenone is a liquid; boiling point or refractive index determination is more appropriate. |
| Refractive Index | Refractometry | Measures refractive index (n20D) at a specified temperature (e.g., 20°C) for rapid identification and preliminary purity screening. |
| Impurity Analysis | GC/HPLC Methods | Evaluates purity based on the number and size of impurity peaks in chromatograms. Can be combined with mass spectrometry for identification of unknown impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects heavy metal residues such as lead, cadmium, and mercury, suitable for pharmaceutical-grade product control. Requires sample digestion prior to analysis. |
Technical Specifications of 3',4',5'-TRIFLUOROACETOPHENONE
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Refractive Index (n20/D) | 1.495–1.505 |
| Relative Density (20°C/25°C) | 1.32–1.36 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3',4',5'-TRIFLUOROACETOPHENONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3',4',5'-TRIFLUOROACETOPHENONE
Safety Information of 3',4',5'-TRIFLUOROACETOPHENONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3',4',5'-TRIFLUOROACETOPHENONE
Industrial 3',4',5'-TRIFLUOROACETOPHENONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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