China Factory Direct
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| CAS number | 220141-74-2 |
| Product name | 2,4,5-Trifluorophenylacetonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., BTK inhibitors) | Introduces the trifluorophenyl moiety via nucleophilic substitution or coupling reactions, commonly employed in constructing fluorinated aromatic rings of active pharmaceutical ingredients |
| Agrochemicals | Used to synthesize novel fluorinated insecticides and fungicides | Serves as a fluorinated side-chain precursor; converted into target agrochemicals through hydrolysis, reduction, cyclization, or related steps |
| Materials Science | Intermediate for synthesizing liquid crystal monomers and organic light-emitting diode (OLED) materials | Undergoes cyano group transformation (e.g., hydrolysis to amide/acid or reduction to amine), followed by further coupling to incorporate the highly electronegative trifluorophenyl group—thereby tuning molecular polarity and charge-carrier transport properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID | Quantification by gas chromatography with flame ionization detection using external standard calibration. |
| Related Substances | GC-MS | Identification and quantification of impurities based on retention time and mass spectral matching. |
| Residual Solvents | GC-FID | Detection and quantification of volatile solvents using headspace GC with FID detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on iodine consumption in a moisture-specific redox reaction. |
| Acidity (as HCl) | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein indicator. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard reference under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Density | Digital Density Meter | Determination of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.465–1.475 |
| Relative Density (20°C/25°C) | 1.28–1.32 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.