(DAP22)-SHK Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 220384-25-8 |
| Product name | (DAP22)-SHK |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (DAP22)-SHK
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (DAP22)-SHK Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (DAP22)-SHK
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Neuropathic pain research | Used as a research tool for developing drugs targeting voltage-gated sodium channels |
| Biomedical | Neuroscience research | Applied as a probe to study voltage-gated sodium channels in neurons |
| Medical research | Drug screening | Used for screening and evaluating novel analgesic compounds |
| Chemical biology | Molecular biology experiments | Employed as a bioactive molecule in studies of diverse cellular functions |
Manufacturing Quality Control of (DAP22)-SHK
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Reversed-Phase HPLC with UV detection | Quantifies SHK content by comparing peak area against a certified reference standard using C18 column and UV absorbance at 220 nm. |
| Related Substances | Reversed-Phase HPLC with gradient elution | Detects and quantifies structurally related impurities (e.g., deamidated or oxidized variants) via retention time and peak area relative to main peak. |
| Residual Solvents | Gas Chromatography with Flame Ionization Detection (GC-FID) | Measures volatile organic solvents (e.g., acetonitrile, methanol) based on retention time and calibrated FID response. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Hg, As) by ionization in plasma and mass-selective detection at isotopic masses. |
| Endotoxin | Kinetic Chromogenic LAL Assay | Measures endotoxin via enzymatic cascade triggered by Limulus amebocyte lysate, yielding colorimetric signal proportional to endotoxin concentration. |
| Biological Activity | Patch-Clamp Electrophysiology (on Kv1.3 channels) | Evaluates functional potency by measuring inhibition of potassium current in transfected mammalian cells expressing human Kv1.3. |
| Peptide Identity | Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) | Confirms molecular weight match to theoretical mass of SHK (4057.8 Da) within ±0.5 Da tolerance. |
| Optical Rotation | Polarimetry | Measures specific rotation at 20 deg C using sodium D-line to verify chiral integrity and correct stereochemistry. |
| pH (1% w/v solution) | Potentiometric pH measurement | Determines hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Particulate Matter | Light Obscuration Particle Counting | Counts and sizes insoluble particles >10 um and >25 um per USP <788> using laser scattering and light blockage principle. |
| Sterility | Membrane Filtration with Fluid Thioglycollate Medium and Soybean-Casein Digest Medium | Confirms absence of viable microorganisms by filtration, incubation, and visual assessment for turbidity/growth over 14 days. |
Technical Specifications of (DAP22)-SHK
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0 to -18.0 deg (c=1, in water) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (DAP22)-SHK
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of (DAP22)-SHK
Industrial (DAP22)-SHK Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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