China Factory Direct
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| CAS number | 220497-61-0 |
| Product name | FMOC-L-CYCLOPENTYLGLYCINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for peptide drug synthesis, used to construct biologically active peptide sequences containing the cyclopentylglycine motif | Employed as an Fmoc-protected amino acid derivative in solid-phase peptide synthesis (SPPS), introduced into the peptide chain via sequential coupling reactions |
| Biochemistry | Non-natural amino acid analog for protein and peptide research, applied in structure–function relationship studies | Incorporated into peptide assembly on automated synthesizers using Fmoc chemistry, followed by deprotection and purification |
| Academic Research | Preparation of novel peptide analogs or molecular probes to investigate the stereochemical effects of the cyclopentyl side chain | Organic synthesis at laboratory scale, involving deprotection, coupling, and purification (e.g., HPLC) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., di-Fmoc derivative, hydrolysis products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies residual metals (e.g., Pd, Ni, Cu) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (700-800 C) and weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Determines particle size distribution in dry powder form using Mie scattering theory with laser diffraction instrumentation. |
| Melting Point | Capillary Melting Point Apparatus | Identifies melting range by observing solid-to-liquid transition under controlled heating rate (1-2 C/min). |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode to assess acidic/basic impurities. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (by LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | -22.0 to -18.0° (c=1, in DMF) |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.