China Factory Direct
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| CAS number | 220497-79-0 |
| Product name | FMOC-D-2-BROMOPHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral drug intermediates | Used as a chiral building block in solid-phase or solution-phase peptide synthesis to prepare peptide-based therapeutics containing D-phenylalanine motifs |
| Biochemistry | Fluorescent labeling and probe development | Leverages the FMOC protecting group to incorporate bromoaromatic rings into peptide sequences, enabling subsequent conjugation with fluorescent dyes or functional modifications |
| Materials science | Preparation of functionalized peptide materials | Serves as a structural monomer in designing functional biomaterials with defined secondary structures; incorporated into target sequences via solid-phase peptide synthesis (SPPS) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 260-280 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., FMOC-D-phenylalanine, deprotected amino acid) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Measures enantiomeric excess by separating D- and L-isomers on a chiral stationary phase and comparing peak areas. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (e.g., Pb, Cd, Ni, Cu) after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Detects and quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Residual Palladium | ICP-MS | Measures trace palladium (from coupling catalysts) after microwave digestion using inductively coupled plasma mass spectrometry for ultra-trace detection. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring mass loss after drying under controlled temperature and vacuum conditions. |
| pH of Solution | Potentiometric Titration | Measures acidity/basicity of aqueous suspension or solution using calibrated pH electrode and standardized acid/base titrant. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry or dispersed state by measuring angular scattering pattern of laser light. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture medium, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | -20.0° to -24.0° (c=1, in DMF) |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.