N-Benzylpiperidine-4-carboxaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22065-85-6 |
| Product name | N-Benzylpiperidine-4-carboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Benzylpiperidine-4-carboxaldehyde
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Benzylpiperidine-4-carboxaldehyde Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Benzylpiperidine-4-carboxaldehyde
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antipsychotic drugs (e.g., risperidone, paliperidone) | Constructs piperidine ring derivatives via reductive amination or condensation reactions for subsequent drug molecule synthesis |
| Chemical Synthesis | Organic building block for constructing complex molecules containing benzylpiperidine motifs | Participates in Wittig reactions, Grignard additions, or reduction reactions to introduce aldehyde functional groups for structural modification |
| Drug Discovery | Used in developing novel central nervous system (CNS) therapeutics and receptor ligands | Serves as a lead compound scaffold; high-activity candidate molecules are identified through structural optimization and screening |
Manufacturing Quality Control of N-Benzylpiperidine-4-carboxaldehyde
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Reversed-phase HPLC (RP-HPLC) is employed, using a C18 column as the stationary phase and methanol/water or acetonitrile/water as the mobile phase. Detection is performed with a UV detector (typically at 254 nm). The assay of the active ingredient is calculated by comparison with a reference standard, offering high sensitivity, accuracy, and reproducibility. |
| Purity Analysis | Gas Chromatography (GC) | Suitable for analyzing volatile components, using a capillary column (e.g., DB-5MS), nitrogen or helium as carrier gas, programmed temperature ramping, and a flame ionization detector (FID). This method effectively separates the main component from impurities and is used for purity assessment. |
| Impurity Analysis | HPLC-MS (Liquid Chromatography-Mass Spectrometry) | Combines the separation capability of HPLC with the structural identification power of mass spectrometry, enabling qualitative and quantitative analysis of unknown impurities, especially suitable for trace impurities and metabolite identification. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structural information, confirming the chemical structure of 1-Benzyl-4-piperidinecarboxaldehyde, including substitution patterns and functional group connectivity. It is considered the gold standard for structural elucidation. |
| Molecular Weight Determination | Mass Spectrometry (MS) | Electrospray Ionization (ESI-MS) or Electron Ionization (EI-MS) is used to detect the molecular ion peak ([M+H]⁺ or M⁺), verifying whether the molecular weight matches the theoretical value (molecular formula: C₁₂H₁₅NO, molecular weight: 189.26). |
| Residual Solvent Testing | Gas Chromatography (GC-FID/MS) | Headspace or direct injection is used to detect residual organic solvents (e.g., ethanol, acetone, toluene) that may remain from the synthesis process, in compliance with ICH Q3A/Q3C guidelines. |
| Moisture Content Determination | Karl Fischer Titration (KF) | Uses volumetric or coulometric Karl Fischer moisture analyzers to accurately measure water content in the sample, ensuring raw material stability and consistency in subsequent processing. |
| Melting Point Determination | Micro Melting Point Apparatus | The melting behavior is observed using a micro melting point apparatus to determine the melting range (typical value approximately 70–75 °C), serving as a preliminary indicator of purity and crystalline state. |
Technical Specifications of N-Benzylpiperidine-4-carboxaldehyde
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Benzylpiperidine-4-carboxaldehyde
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Benzylpiperidine-4-carboxaldehyde
Safety Information of N-Benzylpiperidine-4-carboxaldehyde
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of N-Benzylpiperidine-4-carboxaldehyde
Industrial N-Benzylpiperidine-4-carboxaldehyde Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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