METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 220664-31-3 |
| Product name | METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic intermediate in the preparation of biologically active indole derivatives, including potential antitumor, anti-inflammatory, or neuroactive drug molecules | Employed in organic synthesis reactions—including nucleophilic substitution, Suzuki coupling, reduction, and cyclization—to construct complex molecular frameworks |
| Agrochemical R&D | Applied in the synthesis of lead compounds for novel plant growth regulators or insecticides | Used as a key building block for heterocyclic structure modification and functionalization |
| Organic Synthesis Reagent | Used to build indole derivative libraries containing both bromo and ester functional groups | Leveraged for metal-catalyzed cross-coupling (e.g., Pd-catalyzed C–C bond formation) via the bromo group, or for hydrolysis/ammonolysis transformations of the ester group |
Manufacturing Quality Control of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni) by plasma excitation and optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residual Catalyst (Pd) | ICP-MS | Detects palladium residue at trace levels using inductively coupled plasma mass spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard reference. |
| Specific Optical Rotation | Polarimetry | Measures angle of rotation of plane-polarized light induced by chiral molecules in solution. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after controlled heating under specified conditions. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in aqueous suspension using calibrated glass electrode and pH meter. |
Technical Specifications of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
Safety Information of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE
Industrial METHYL 3-BROMO-1H-INDOLE-2-CARBOXYLATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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