China Factory Direct
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| CAS number | 2210-93-7 |
| Product name | 1-PHENYLPIPERAZINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for central nervous system (CNS) drugs, used in the synthesis of antidepressants, anxiolytics, and dopamine receptor modulators (e.g., precursor to aripiprazole) | Condensed with acyl chlorides or aldehydes/ketones under basic conditions; target molecular scaffold constructed via subsequent reduction or cyclization; hydrochloride salt form facilitates purification and storage |
| Pharmaceuticals | Research tool compound for 5-HT1A/2A receptor antagonism studies | Dissolved directly in buffer solution (e.g., PBS) for in vitro receptor binding assays and cellular functional testing |
| Chemicals | Building block for novel functional materials, used to synthesize nitrogen-containing heterocyclic optoelectronic materials | Condensed with aromatic aldehydes to form Schiff bases, followed by metal coordination or electrochemical polymerization to prepare organic semiconductor thin films |
| Agrochemicals | Potential structural motif for insecticides/fungicides (in early-stage structure–activity relationship studies) | Introduced as the core heterocyclic scaffold into triazole- or pyrimidine-based derivatives; biological activity enhanced through substituent optimization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., aniline, benzaldehyde, 1-phenylpiperazine) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, offering sub-ppq detection limits and compliance with ICH Q3D. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration from hydrochloride salt counterion. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharp melting range confirms crystallinity and absence of significant impurities. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Scale | Subjective visual assessment against water standard; APHA color scale quantifies yellowness/browning due to degradation. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700–800 °C followed by weighing of inorganic residue to assess inorganic ash content. |
| Microbial Contamination | Membrane Filtration / TSA/SDA | Enumeration of aerobic bacteria, yeasts, and molds using validated membrane filtration and growth on tryptic soy agar/sabouraud dextrose agar. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values relevant for processability and dissolution. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral integrity (though compound is achiral, detects chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white fine crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 245-249°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.