China Factory Direct
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| CAS number | 221121-37-5 |
| Product name | 4-(4-FLUORO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Intermediates | Synthesis of drug molecule scaffolds | Prepared via organic synthesis reactions, typically involving nucleophilic substitution and reductive amination |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220-254 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and/or spiked reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, ethyl acetate) via headspace GC with flame ionization detection using calibrated external standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol-based reagent. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid content by titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Heavy Metals (as Pb) | ICP-OES | Quantifies total heavy metals (Pb, Cd, Ni, Cr, etc.) after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by incinerating sample at 600-750 C and weighing residual non-volatile residue. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light source to assess chiral purity and enantiomeric excess. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against defined standards (e.g., clear, colorless to pale yellow liquid) under controlled lighting. |
| Density | Digital Density Meter | Determines mass per unit volume at specified temperature (e.g., 20 C) using oscillating U-tube principle with temperature-controlled measurement. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.520–1.530 |
| Relative Density (20°C/25°C) | 1.12–1.14 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.