China Factory Direct
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| CAS number | 22198-72-7 |
| Product name | 4-AMINOANTIPYRINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Environmental Monitoring | Colorimetric determination of phenolic compounds in water | Reacts with phenolic compounds in the presence of an oxidant (e.g., potassium ferricyanide) to form a red quinone imine dye; absorbance is measured by spectrophotometry |
| Clinical Diagnostics | Enzymatic colorimetric analysis of metabolites (e.g., creatinine, glucose) in serum or urine | Serves as a chromogen in peroxidase-coupled reactions, generating colored products for quantitative detection in the presence of H₂O₂ |
| Pharmaceutical Industry | Pharmaceutical intermediate | Used in synthesizing antipyretic-analgesic antipyrine derivatives and structural modification of certain anti-inflammatory drugs |
| Analytical Chemistry | Organic analytical reagent | Applied in colorimetric titration or spectrophotometric analysis of metal ions (e.g., iron, cobalt, nickel), forming stable colored complexes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (purity) | UV-Vis Spectrophotometry | Quantifies 4-aminoantipyrine hydrochloride based on absorbance at characteristic wavelength (e.g., ~290 nm) using Beer-Lambert law. |
| Loss on Drying | Gravimetric (Thermogravimetry) | Measures mass loss after drying at specified temperature (e.g., 105 C) to determine volatile content including moisture and residual solvents. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Determines inorganic impurities by igniting sample at high temperature (e.g., 700-800 C) and weighing residual ash. |
| Chloride Content | Potentiometric Titration with AgNO3 | Quantifies chloride ions via argentometric titration using silver nitrate and a silver indicator electrode. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Measures total heavy metal content (expressed as lead) after acid digestion and atomization in flame or graphite furnace. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally related impurities (e.g., 4-aminoantipyrine, degradation products) using reversed-phase chromatography. |
| pH of Solution | Potentiometric pH Measurement | Determines acidity/basicity of aqueous solution (e.g., 1% w/v) using calibrated pH electrode. |
| Sulfate Content | Gravimetric (Barium Sulfate Precipitation) | Precipitates sulfate as BaSO4 and determines mass after filtration and drying. |
| Iron (Fe) Content | ICP-OES | Quantifies iron after acid digestion by measuring atomic emission intensity at characteristic wavelength. |
| Appearance (Color and Clarity) | Visual Inspection | Assesses physical state, color (white to off-white), and clarity of solid or its aqueous solution against standard references. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range at which solid transitions from crystalline to liquid phase using calibrated apparatus. |
| Water Content | Karl Fischer Titration | Quantifies water via stoichiometric reaction with iodine in methanol-based reagent, detected electrometrically. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 126-130°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.