China Factory Direct
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| CAS number | 22252-43-3 |
| Product name | 7-Amino-3-methyl-3-cephem-4-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for β-lactam antibiotics | Used in the synthesis of cephalosporin antibiotics; involved in cyclization, acylation, and other reactions to produce active pharmaceutical ingredients |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual inspection, physical constant determination | Observe appearance (e.g., white to off-white crystalline powder), solubility, melting point, and other physical properties. |
| Identification | Infrared Spectroscopy (IR), HPLC retention time comparison | Compare the infrared absorption spectrum or high-performance liquid chromatography retention time with a reference standard to confirm structural consistency. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC with gradient elution and ultraviolet detection (around 254 nm) to separate and quantify related impurity peaks. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | External standard method or area normalization method. Use a C18 column with a phosphate buffer-organic mobile phase system to determine the content of the main component. |
| Moisture | Karl Fischer Titration | Determine the moisture content using potentiometric or volumetric titration, ensuring compliance with loss on drying or moisture limit requirements. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC with FID detection to analyze residual solvents such as ethanol and acetone according to ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine the presence of heavy metals (e.g., lead, cadmium, mercury, arsenic) after digestion, ensuring compliance with pharmacopoeia limits. |
| pH Value | pH Meter Measurement | Prepare a solution of specified concentration and measure its pH using a calibrated pH meter to control the acidity/alkalinity for stability. |
| Specific Rotation | Polarimeter Measurement | Prepare a solution of specified concentration and measure its optical rotation at a specified wavelength (usually 589 nm) to verify optical purity. |
| Bacterial Endotoxins | Limulus Amebocyte Lysate (LAL) Test | Used for injectable raw materials to detect pyrogenic substances, ensuring safety requirements for sterile preparations. |
| Microbial Limit | Plate Count Method / Membrane Filtration Method | Perform total aerobic bacteria, mold, and yeast counts and control organism testing according to general monograph methods in pharmacopoeia. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 162–166°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.