China Factory Direct
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| CAS number | 22280-60-0 |
| Product name | 6-Chloro-2-methyl-3-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used in the synthesis of antiviral drugs |
| Pesticides | Insecticide intermediate | Used in the synthesis of novel organophosphorus insecticides |
| Chemical manufacturing | Synthetic raw material | Served as a feedstock for nitration reactions |
| Materials science | Functional material precursor | Applied in the preparation of conductive polymers or functional coatings |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a UV detector (e.g., 254 nm or 280 nm), quantifying the main component's purity by retention time and peak area. The mobile phase is usually acetonitrile-water or methanol-buffer salt system. |
| Related Substances / Impurity Testing | HPLC (Gradient Elution) | Uses a gradient elution program to separate potential process impurities or degradation products, confirming structures by comparing retention times with reference standards or using LC-MS. |
| Content Determination | HPLC External Standard Method / Internal Standard Method | Establishes a standard curve using known concentration reference standards, calculating content through sample peak area, ensuring accurate and reliable results. The internal standard method reduces injection errors. |
| Moisture Content Determination | Karl Fischer Titration | Measures trace moisture using volumetric or coulometric methods, suitable for thermally unstable or hygroscopic organic compounds. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | The volatile solvents in the sample are volatilized by heating and analyzed by gas chromatography, with FID or MS detectors quantifying residual organic solvents (e.g., methanol, ethyl acetate, DMF). |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Determines the temperature range of the solid-to-liquid transition, used to preliminarily assess purity and crystalline consistency. |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | NMR (¹H/¹³C) confirms the hydrogen and carbon skeleton; IR verifies functional groups (e.g., nitro group, pyridine ring); MS determines molecular weight and fragment characteristics to confirm the structure. |
| Heavy Metal Detection | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After sample digestion, it detects residual heavy metals such as lead, cadmium, mercury, and arsenic, meeting ICH Q3D or pharmacopoeia requirements. |
| Drying Loss | Drying Weight Loss Method | Dries the sample at a specific temperature (e.g., 105°C) until constant weight, calculating the percentage of mass loss to evaluate volatile components or adsorbed water content. |
| Specific Rotation (if applicable) | Optical Rotatory Dispersion Measurement | If there are chiral centers or optical active impurities, the specific rotation should be measured to assess optical purity (this item is typically not applicable for this compound, which has no chiral center). |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 68–72°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.