(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22348-32-9 |
| Product name | (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral catalyst | Used in asymmetric synthesis reactions, such as asymmetric alkylation and epoxidation of aldehydes and ketones, to construct chiral centers |
| Organic synthesis | Chiral ligand | Forms complexes with metals (e.g., Ti, Cu, Zn) for asymmetric catalytic hydrogenation and carbon–carbon bond formation reactions |
| Fine chemicals | Intermediate | Serves as a key intermediate in synthesizing other chiral amines or proline derivatives, used to prepare optically active functional molecules |
Manufacturing Quality Control of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder or crystals), presence of caking, or visible impurities. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase C18 column and a UV detector (e.g., 254 nm) to determine the purity of the main peak using an external standard method or area normalization method. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column (e.g., Chiralpak AD-H, AS-H) to separate enantiomers and determine the enantiomeric excess (ee value) of the (R)-isomer. |
| Specific Optical Rotation | Polarimetry | Prepare a solution in a specified solvent (e.g., methanol or ethanol), measure the [α]D value using a sodium lamp (589 nm) at a defined temperature, and compare with literature values (typically +20° to +30°). |
| Melting Point | Melting Point Apparatus (Capillary method or DSC) | Determine the melting temperature range of the compound to assess purity and polymorphic consistency; typical melting point is around 120–125°C (may vary slightly depending on source). |
| Solubility | Solubility Test | Test solubility in various solvents (e.g., water, ethanol, diethyl ether, ethyl acetate, dichloromethane) to meet specified criteria. |
| Water Content | Karl Fischer Titration | Determine the total amount of free and bound water to ensure it remains within acceptable limits (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents potentially present from the manufacturing process in accordance with ICH guidelines (e.g., methanol, ethanol, ethyl acetate, dichloromethane). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual levels of toxic metal elements such as lead, mercury, cadmium, and arsenic, meeting pharmacopoeia or client specifications (typically ≤10 ppm). |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Determine the amount of non-volatile inorganic residue after high-temperature carbonization and sulfuric acid treatment to assess inorganic impurity levels. |
Technical Specifications of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +65.0 to +68.0 deg (c=1, in CHCl3) |
| Melting Point | 128.0 to 132.0 °C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
Safety Information of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
Industrial (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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