Fmoc-His(Clt)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 224032-19-3 |
| Product name | Fmoc-His(Clt)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-His(Clt)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-His(Clt)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-His(Clt)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Peptide synthesis (Fmoc-based solid-phase amino acid protection) | Used in solid-phase peptide synthesis (SPPS) |
| Biotechnology | Protein structural analysis and modification | Applied in chemical conjugation and labeling |
| Pharmaceutical R&D | Preparation of peptide drug intermediates | Used in solution-phase synthesis and purification |
Manufacturing Quality Control of Fmoc-His(Clt)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at 268 nm using reverse-phase C18 column and gradient elution with aqueous/organic mobile phase. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., dipeptides, deletion sequences, deprotection by-products) via retention time comparison and peak area normalization. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, MeOH) using headspace sampling and flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine generated electrochemically in pyridine/methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Measures palladium from coupling catalysts post-digestion using inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D | Measures specific rotation at 589 nm using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension via angular scattering pattern analysis. |
| pH (1% w/v solution) | Potentiometric Titration | Evaluates acidity/basicity of aqueous solution using calibrated pH electrode and standardized acid/base titrant. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions after sample dissolution using suppressed conductivity detection and anion-exchange column. |
| Residual TFA | GC-FID | Detects trifluoroacetic acid from cleavage/deprotection steps via direct injection or headspace GC with FID. |
| Microbial Limits | Membrane Filtration | Assesses total aerobic microbial count and absence of specified pathogens (e.g., E. coli, S. aureus) using selective agar media. |
Technical Specifications of Fmoc-His(Clt)-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +72.0 to +76.0° (c=1, DMF) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-His(Clt)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-His(Clt)-OH
Packaging of Fmoc-His(Clt)-OH
Industrial Fmoc-His(Clt)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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