China Factory Direct
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| CAS number | 22454-86-0 |
| Product name | CALCIUM OROTATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Food Industry | Nutritional fortificant (calcium source); dietary supplement ingredient | Added as a calcium fortificant to dairy products, infant formula, and breakfast cereals, with usage levels compliant with GB 14880-2012 “National Food Safety Standard – Usage Standard for Food Nutrient Fortificants” |
| Pharmaceutical Industry | Calcium supplement for therapeutic use; component of multivitamin and mineral formulations | Used in the preparation of oral calcium tablets, capsules, or solutions, formulated into solid dosage forms via wet granulation or direct compression |
| Dietary Supplements | Raw material for calcium dietary supplements | Blended with other vitamins (e.g., vitamin D3) and minerals, then processed into health food products via mixing, granulation, tablet compression, or capsule filling |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Calcium Orotate Content) | HPLC-UV | Quantification based on retention time and UV absorbance at 260 nm using a C18 column and aqueous mobile phase. |
| Calcium Content | EDTA Titration | Complexometric titration with standardized EDTA solution; calcium forms a stable 1:1 complex detected by Eriochrome Black T indicator. |
| Heavy Metals (Pb, Cd, As, Hg) | ICP-MS | Multi-element detection via plasma ionization and mass spectrometric separation; offers sub-ppt sensitivity. |
| Loss on Drying | Gravimetric (105 C) | Mass loss measured after drying to constant weight at 105 C under controlled atmospheric conditions. |
| Residue on Ignition | Gravimetric (550 C) | Inorganic residue mass determined after high-temperature ashing at 550 C in a muffle furnace. |
| Chloride Impurity | Argentometric Titration (Mohr method) | Titration with silver nitrate; endpoint detected by reddish-brown Ag2CrO4 precipitate formation. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Precipitation of sulfate as BaSO4 in acidic medium; turbidity measured spectrophotometrically at 420 nm. |
| pH (1% aqueous solution) | Potentiometric (pH meter) | Hydrogen ion activity measured using calibrated glass electrode in a 1% w/v aqueous suspension. |
| Microbial Limits (Total Aerobic Count) | Plate Count Agar (PCA) Method | Viable aerobic microorganisms enumerated by colony formation on nutrient agar after incubation at 30-35 C for 3-5 days. |
| Yeast and Mold Count | Sabouraud Dextrose Agar (SDA) Method | Fungal enumeration by colony formation on selective SDA medium after incubation at 20-25 C for 5-7 days. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine volume-based particle size distribution. |
| Organic Volatile Impurities | GC-FID | Separation and quantification of residual solvents using gas chromatography with flame ionization detection. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=10 ppm |
| Odor | Characteristic, mild |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.