China Factory Direct
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| CAS number | 22457-89-2 |
| Product name | Benfotiamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticides | Used as an intermediate in the production of organophosphorus insecticides |
| Pharmaceuticals | Drug synthesis | Employed as an intermediate in the synthesis of certain pharmaceuticals |
| Chemical manufacturing | Organic synthesis | Served as a raw material for synthesizing organic sulfur compounds |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Perform infrared scanning of the sample and reference standard within the range of 4000–400 cm⁻¹, and compare characteristic absorption peaks to confirm molecular structural consistency. |
| High-Performance Liquid Chromatography (HPLC) | Confirm identity by comparing retention times—verify that the chromatographic peak of benphosphthiamine in the sample matches that of the reference standard for qualitative identification. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 246 nm or 275 nm), and quantify the main component using external or internal standard methods. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient elution to separate impurities, detect degradation products or synthesis intermediates, calculate individual impurity peak areas, and assess purity. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace sampling to detect residual organic solvents (e.g., methanol, ethanol, acetone) from manufacturing processes, ensuring compliance with pharmacopoeial limits. |
| Water Content | Karl Fischer Titration | Accurately determine water content in the sample via electrochemical titration; suitable for quality control of solid samples with low moisture levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure elemental concentrations of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical safety standards. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Measure the particle size distribution of the active pharmaceutical ingredient, which affects solubility and bioavailability; commonly used for pre-formulation quality assessment. |
| Polymorphic Form Analysis | X-Ray Powder Diffraction (XRD) | Analyze the crystal structure of benphosphthiamine to ensure batch-to-batch consistency in crystalline form, avoiding differences in stability or dissolution due to polymorphic variation. |
| Melting Point | Melting Point Determination | Determine the melting temperature range using a melting point apparatus; serves as a physical property identifier and an indicator of purity. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.