2-Chloro-5-methylpyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22536-61-4 |
| Product name | 2-Chloro-5-methylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-methylpyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-methylpyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-methylpyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of insecticide and fungicide intermediates | Used as a key structural unit in nucleophilic substitution reactions to construct chloropyrimidine rings in active ingredients, such as neonicotinoid intermediates (e.g., imidacloprid, acetamiprid) |
| Pharmaceuticals | Synthesis of antiviral and antitumor drug intermediates | Applied in coupling reactions and metal-catalyzed cross-coupling (e.g., Suzuki, Buchwald–Hartwig) to introduce the pyrimidine scaffold for preparing protein kinase inhibitors or antiviral lead compounds |
| Dyes & Pigments | Synthesis of specialty functional dye intermediates | Employed as a heterocyclic component in condensation reactions to build pyrimidine-based dyes or fluorescent labels with optoelectronic properties |
| Chemical Reagents | Synthesis of organic building blocks | Utilized as a chlorinated heterocyclic reagent to construct nitrogen-containing heterocycles, enabling preparation of multifunctional intermediates via amino substitution, alkylation, and related transformations |
Manufacturing Quality Control of 2-Chloro-5-methylpyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under validated chromatographic conditions. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reverse-phase C18 column and gradient elution with UV absorbance measurement at 254 nm. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile organic solvents are extracted into headspace and quantified by GC-FID using internal standard calibration. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Anionic separation on ion-exchange column followed by quantitative detection of chloride via suppressed conductivity. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Element-specific detection after acid digestion and dilution, based on mass-to-charge ratio and isotopic abundance. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Sample is ignited at 600-700 C, cooled in desiccator, and weighed to determine non-volatile inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid transforms to liquid under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral compounds in solution at specified concentration and path length. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity determined using calibrated glass electrode and reference electrode in aqueous suspension or saturated solution. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Analysis of angular scattering pattern of laser beam passing through dispersed sample to calculate size distribution by Mie theory. |
| Bulk Density | ASTM D1895 Method A (Tapped Density) | Mass per unit volume measured after mechanically tapping a graduated cylinder containing the powder to achieve settled state. |
Technical Specifications of 2-Chloro-5-methylpyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-methylpyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-methylpyrimidine
Packaging of 2-Chloro-5-methylpyrimidine
Industrial 2-Chloro-5-methylpyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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