2,5-Dichloropyrimidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 22536-67-0 |
| Product name | 2,5-Dichloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 2,5-Dichloropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-Dichloropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-Dichloropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate for antiviral drugs (e.g., efavirenz) | Introduces arloxy or arylamino groups at the 4-position of the pyrimidine ring via nucleophilic substitution to construct the active molecular scaffold |
| Agrochemicals | Intermediate for the fungicide mepanipyrim | Aminates 2,5-dichloropyrimidine to synthesize pyrimidinylamine compounds with antimicrobial activity |
| Agrochemicals | Intermediate for the acaricide pyriminostrobin | Undergoes etherification or further functionalization to prepare active molecules for mite control |
| Organic Synthesis | Versatile building block for constructing complex pyrimidine derivatives | Enables sequential, selective coupling reactions (e.g., Suzuki coupling, Buchwald–Hartwig amination) leveraging differential reactivity of the C-2 and C-5 chlorine atoms |
Manufacturing Quality Control of 2,5-Dichloropyrimidine
| Milestone Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase column (e.g., C18) is used, with methanol/water or acetonitrile/buffer as the mobile phase. The UV detector (~254 nm) quantifies the main component purity. This method is suitable for samples with a content of ≥98%. |
| Impurity Analysis | HPLC or GC-MS | HPLC is used for separation of non-volatile impurities; GC-MS is suitable for identification and semi-quantitative analysis of volatile organic impurities, with unknown impurities identified by matching with mass spectrometry libraries. |
| Moisture Content | Karl Fischer Titration (KF Titration) | Measures trace water using either volumetric or coulometric methods. Suitable for moisture-sensitive organic synthesis intermediates, with results accurate to the ppm level. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | The volatile solvents in the sample are vaporized by heating, then separated by a capillary column and quantified by FID or MS detectors (e.g., toluene, DMF). |
| Structure Confirmation | Proton Nuclear Magnetic Resonance (¹H NMR) | Hydrogen chemical shifts and coupling constants are measured in deuterated solvents (e.g., CDCl₃), confirming the molecular structure and substitution positions to match the target compound. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | The initial and final melting temperatures are observed during heating, which can be used to assess the purity and crystal form consistency of the substance. A standard melting point range serves as a quality control criterion. |
| Appearance and Color | Visual Colorimetry / Colorimeter | White to slightly white crystalline powder is considered acceptable. For quantitative evaluation, a colorimeter can measure L*a*b* values and compare them with the standard to control color deviation. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After acid digestion, the residual levels of heavy metals such as lead, cadmium, mercury, and arsenic are detected, meeting the limits set by ICH Q3D or pharmacopoeia for elemental impurities. |
Technical Specifications of 2,5-Dichloropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 54.0–56.0 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 2,5-Dichloropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-Dichloropyrimidine
Packaging of 2,5-Dichloropyrimidine
Industrial 2,5-Dichloropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply