5-CHLOROMETHYL-2-OXAZOLIDINONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22625-57-6 |
| Product name | 5-CHLOROMETHYL-2-OXAZOLIDINONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-CHLOROMETHYL-2-OXAZOLIDINONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-CHLOROMETHYL-2-OXAZOLIDINONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-CHLOROMETHYL-2-OXAZOLIDINONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antifungal agents such as amorolfine | Produced via reaction of 2-oxazolinone with chloromethylating reagents (e.g., paraformaldehyde/HCl or chloromethyl methyl ether) under acidic conditions, followed by subsequent coupling and reduction steps to construct the amorolfine molecular scaffold |
| Agrochemical R&D | Potential structural motif for fungicides and insecticides, used to build biologically active molecules containing an oxazoline ring | Employed as a heterocyclic building block in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling introduction of substituted aryl or alkenyl side chains to optimize biological activity |
| Organic Synthesis | Multifunctional chiral synthon for constructing complex nitrogen- and oxygen-containing heterocycles | Used as a substrate in asymmetric alkylation, cycloaddition, or nucleophilic substitution reactions; its chloromethyl group can be efficiently displaced by hydroxyl, amino, azido, and other functional groups for diversity-oriented synthesis |
Manufacturing Quality Control of 5-CHLOROMETHYL-2-OXAZOLIDINONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion; detection based on mass-to-charge ratio of metal ions in plasma ionization source. |
| Chloride Ion Impurity | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection; chloride quantified via calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against specified criteria (e.g., white to off-white crystalline powder). |
| Loss on Drying | Gravimetric Heating | Mass loss measured after drying under specified temperature/vacuum conditions; reflects volatile content including residual solvents and moisture. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light by chiral compound in solution; used to confirm stereochemical integrity. |
| Residue on Ignition | Sulfated Ash Test | Weight of non-volatile residue after high-temperature incineration in presence of sulfuric acid; indicates inorganic impurities. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH measured in defined water/solvent suspension using calibrated glass electrode; reflects acidic/basic degradation products. |
Technical Specifications of 5-CHLOROMETHYL-2-OXAZOLIDINONE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 112-116°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-CHLOROMETHYL-2-OXAZOLIDINONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-CHLOROMETHYL-2-OXAZOLIDINONE
Safety Information of 5-CHLOROMETHYL-2-OXAZOLIDINONE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-CHLOROMETHYL-2-OXAZOLIDINONE
Industrial 5-CHLOROMETHYL-2-OXAZOLIDINONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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