(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22677-21-0 |
| Product name | (R)-(+)-4-HYDROXY-2-PYRROLIDINONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(+)-4-HYDROXY-2-PYRROLIDINONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediates | Used in the synthesis of biologically active chiral drug molecules; employed in asymmetric synthesis reactions |
| Organic Synthesis | Organic synthesis reagents | Applied as building blocks for constructing complex molecular structures; involved in organic reactions such as cyclization and condensation |
| Biochemical Research | Enzyme inhibitor research | Utilized in the design and development of inhibitors targeting specific enzymes; supports mechanistic studies |
Manufacturing Quality Control of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and calculates ee from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents using gas chromatography with flame ionization detection against calibration standards. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities using gradient HPLC-UV with forced degradation samples for method validation. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid or solution against defined standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Thermogravimetry | Measures weight loss after drying under specified temperature/vacuum conditions to determine volatile content. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in aqueous suspension using calibrated pH electrode and standardized buffer solutions. |
Technical Specifications of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 74.0–77.0°C |
| Optical Rotation | +57.0 to +61.0° (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Safety Information of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Industrial (R)-(+)-4-HYDROXY-2-PYRROLIDINONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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