2-Aminomethyl-3-chloropyrazine HCl Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 22680-44-0 |
| Product name | 2-Aminomethyl-3-chloropyrazine HCl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Aminomethyl-3-chloropyrazine HCl
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Aminomethyl-3-chloropyrazine HCl Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Aminomethyl-3-chloropyrazine HCl
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, or neuroactive compounds | Serves as an amination or coupling reagent precursor in organic synthesis |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of heterocyclic compounds with insecticidal or fungicidal activity | Applied to construct the piperazine-based molecular scaffold of agrochemicals via substitution or condensation reactions |
| Chemical Research | Used to build compound libraries containing chloropyrazine motifs for drug screening and structure–activity relationship (SAR) studies | Employed in multicomponent reactions, palladium-catalyzed cross-coupling, and other synthetic methodologies |
Manufacturing Quality Control of 2-Aminomethyl-3-chloropyrazine HCl
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., starting materials, dechlorinated analogs, dimers) using gradient HPLC/UPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry or optical emission spectrometry. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate using a silver indicator electrode; endpoint determined by potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Ignition at 700–800 °C followed by weighing to determine inorganic ash content as % w/w. |
| pH (1% aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity in a 1% (w/v) aqueous solution using calibrated pH electrode and buffer standards. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation using a digital polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values per ISO 13320. |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per Ph. Eur. 2.6.12/2.6.13. |
| Residual Catalyst (e.g., Pd) | ICP-OES | Quantification of palladium or other metal catalyst residues after microwave-assisted acid digestion using plasma emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
Technical Specifications of 2-Aminomethyl-3-chloropyrazine HCl
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Aminomethyl-3-chloropyrazine HCl
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Aminomethyl-3-chloropyrazine HCl
Safety Information of 2-Aminomethyl-3-chloropyrazine HCl
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Aminomethyl-3-chloropyrazine HCl
Industrial 2-Aminomethyl-3-chloropyrazine HCl Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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