China Factory Direct
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| CAS number | 22744-12-3 |
| Product name | 2-(4-(methoxycarbonyl)phenyl)acetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing angiotensin II receptor blockers (e.g., losartan analogues) | Introduces the arylacetic acid structure via ester hydrolysis, coupling reactions, or cross-coupling reactions (e.g., Suzuki coupling) |
| Pesticides | Structural building block for synthesizing novel herbicides or plant growth regulators | Participates in amidation or esterification reactions as a carboxylic acid derivative to construct the active molecular scaffold |
| Chemical Industry | Monomer or modifier for synthesizing polymeric materials | Introduces aromatic carboxylic acid groups via transesterification or polymerization to enhance material polarity and thermal stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., hydrolysis products, starting materials) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS or AAS | Quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion; ICP-MS offers multi-element trace-level sensitivity, AAS provides single-element accuracy. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of inorganic residue to assess inorganic impurities and ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral impurities (though compound is achiral, confirms absence of optically active contaminants). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values, relevant for handling and formulation performance. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions via suppressed conductivity detection (IC) or argentometric titration with AgNO₃. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample with sulfuric acid pretreatment followed by residue weighing to assess metallic sulfate impurities. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.