5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 228410-90-0 |
| Product name | 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antiviral agents (e.g., HCV NS5A inhibitors) | Constructs the pyridone core structure via multi-step reactions including reduction, cyclization, and coupling |
| Pesticide R&D | Structural modification unit for novel insecticides and fungicides | Introduces bromo, nitro, and methyl functional groups to optimize biological activity and metabolic stability |
| Organic Synthesis | Multifunctional heterocyclic building block for cross-coupling reactions (e.g., Suzuki, Heck) | Undergoes C–Br bond activation and coupling with aryl boronic acids or alkenes under palladium catalysis |
Manufacturing Quality Control of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time separation and UV response relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection against certified standards. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine-sulfur dioxide reaction stoichiometry. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg) by plasma ionization and mass spectrometric detection with isotopic resolution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion with sulfuric acid treatment and high-temperature ashing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting and against standard reference. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after ignition at specified temperature in a muffle furnace. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compounds using plane-polarized light, indicating enantiomeric composition if applicable. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles by analyzing angular scattering pattern of laser beam passing through dispersed sample. |
Technical Specifications of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
Safety Information of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE
Industrial 5-BROMO-2-HYDROXY-3-NITRO-4-PICOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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