China Factory Direct
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| CAS number | 228857-58-7 |
| Product name | Boc-D-Azetidine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of antibiotics, antiviral agents, and other active pharmaceutical ingredients | Applied in asymmetric synthesis and chiral resolution |
| Drug Discovery | Used to construct azetidine scaffolds for developing targeted therapeutics, such as protease inhibitors | Applied in organic synthesis and structural modification |
| Fine Chemicals | Used to produce high-value chiral compounds for applications as catalysts or ligands | Applied in catalytic reactions and functional group transformations |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess (ee). |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., MeOH, EtOAc, THF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Quantification of residual Pd from catalytic hydrogenation steps via inductively coupled plasma optical emission spectrometry after sample digestion. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Residual BOC Reagent | GC-MS | Gas chromatographic separation followed by mass spectrometric detection to identify and quantify residual di-tert-butyl dicarbonate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter under controlled white-light illumination. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | [alpha]D Measurement | Measurement of rotation of plane-polarized light at 589 nm using sodium D-line, normalized to concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine volume-based particle size distribution (D10, D50, D90). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -25.0 to -29.0 deg (c=1, in CHCl3) |
| Melting Point | 85 to 89 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.