China Factory Direct
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| CAS number | 22892-96-2 |
| Product name | 4-Chloro-3-nitro-5-sulphamoylbenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of active ingredients such as antimicrobial and anti-inflammatory agents | Synthesized via process steps including sulfonation, nitration, and chlorination |
| Dyes | Used as an intermediate in the production of azo dyes or other high-performance dyes | Coupled with other aromatic compounds to form chromophores |
| Agricultural Chemicals | Used as an intermediate in the synthesis of herbicides or insecticides | Converted into active ingredients through functional group modifications such as esterification or amidation |
| Research Reagents | Used as a reference standard or reaction substrate in organic synthesis or analytical chemistry | Purified and used directly in laboratory research |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Test | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and a UV detector (e.g., 254 nm or set according to the maximum absorption wavelength). Quantifies the purity of the main component using external standard method or area normalization method. The mobile phase is typically a buffer salt–organic solvent system (e.g., phosphate buffer/acetonitrile). |
| Related Substances (Impurities) | HPLC with Gradient Elution | Employs a gradient elution program to separate the main peak from potential process impurities and degradation products. The relative content of each impurity is calculated based on peak areas, ensuring compliance with pharmacopoeial or internal quality standards. |
| Assay | HPLC External Standard Method / Potentiometric Titration | HPLC External Standard Method: A calibration curve is established using a reference standard of known concentration to calculate sample content. Potentiometric Titration: Based on the neutralization reaction between carboxylic acid groups and alkali; the endpoint is determined by a potential jump, suitable for assay of active pharmaceutical ingredients. |
| Loss on Drying | Drying to Constant Weight at 105°C | A weighed sample is dried at 105°C until constant weight is achieved. The percentage weight loss is calculated to assess moisture and volatile content. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ashing (600–800°C) | The sample is completely ashed in a muffle furnace at high temperature. The residual inorganic matter is weighed to monitor inorganic impurities or catalyst residues. |
| Heavy Metals | Heavy Metals Test as per Chinese Pharmacopoeia (Method I) | After digestion of the sample, it reacts with thioacetamide reagent to produce coloration. The intensity is compared with that of a lead standard solution to ensure total heavy metals (calculated as Pb) do not exceed specified limits. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Headspace or direct injection is used, with separation on capillary columns such as DB-624, and detection by FID or MS to quantify common residual organic solvents (e.g., methanol, ethyl acetate, DMF, etc.). |
| pH Value | pH Meter Measurement | Aqueous solution of defined concentration (e.g., 1% w/v) is prepared. After calibrating the pH meter, the pH is measured directly to reflect acidity/basicity and possible presence of free acid or salt forms. |
| Melting Point | Capillary Melting Point Apparatus | A digital melting point apparatus is used to observe the temperature range from initial melting to complete melting, assessing crystalline purity and structural consistency. |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | IR confirms characteristic functional group absorption peaks; ¹H/¹³C NMR analyzes hydrogen and carbon environments; MS (ESI or EI) verifies molecular ion and fragment ions. Used collectively to confirm chemical structure. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 212–216 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.